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How are those nasty fat pads! They are called adiposity, perhaps because they are exactly where they should not! Eliminate them is very difficult, because our lipid reserves, contained in adipocytes in the form of tiny droplets, are protected by a membrane (the PERILIPINA) which hinders access of the enzyme degreaser (the lipase).

Fortunately the Perilipina is amended forskolin, by a process of phosphorylation.

Result: If the Perilipina the lipase is phosphorylated is able to pass through, thus to dissolve fat, wherever they are located.
  

     

THE COLEUS FORSKOHLII
 

It is a plant of eastern origin, which belongs to the family Labiatae. It grows wild in subtropical areas and is used for centuries by traditional medicine.
From its roots extracts today the purified active substance, called forskolin, which modern scientists have now clarified the chemical structure is that the various health properties. This is due to several studies - the most important are recent - published in the most prestigious international journals. We are talking about a substance that can greatly help those who struggle daily against the overweight and those unsightly fat deposits, which experts define adiposity, but in common parlance are called simply, if a little 'improperly cellulite.

The forskolin acts by stimulating an enzyme called adenylate cyclase body, which produces, in our cells, a biological substance called cyclic AMP (cAMP).


Action, therefore, entirely physiological, and therefore absolutely not harmful to the organism. CAMP is one of the most important mediators for our metabolism, in particular as regards the fatty substances or lipids. The cyclic AMP, in fact, active in turn another enzyme body, indicated with the abbreviation PKA, which is fundamental for the purposes of that process that goes under the name of Lipolysis. We are talking about the chemical reaction that leads to the dissolution of triglycerides (lipids), is that their demolition inside the cell.
A passage absolutely essential if you want to reduce fat mass and increase lean body mass!


It 'clear that, when we put on a diet to lose weight, the mechanism of lipolysis has to work like a Swiss watch. This is the role of forskolin!
 

And that's not the only benefit offered from the root of Coleus.

The forskolin increases, inter alia, the secretion of two proteins, which are called, respectively, Leptin and PYY. These are two substances that the body produces its own, and that since diminishes the hunger, should not some scarce when you want to lose a few extra pounds.


Leptin - the name derives from the greek Leptos which means skinny - is produced by our own deposits of "meat". Its function is to regulate their hunger, telling the brain when it is appropriate to eat less.

The PYY has a similar role, one that is produced by our digestive tract.

And 'as if they were "chemical messages" that give a stop appetite. What this very important for dieters. If, driven by hunger pangs, we steal from the fridge at night than during the day in which we gave up (perhaps with interest), we risk ruin all our efforts.



THE BERBERIS ARISTATA
 

It 'a medicinal plant of the family of Berberidacee, better known as Barberry. It is a shrub erected, the top one to three meters, that forms the beautiful berries coral color. The leaves and fresh shoots are edible, while the juice of the fruits you can prepare a tasty vinegar. Grows spontaneously in all regions of Italy. Already known for some time as part of Traditional Medicine, this plant is now widely studied by scientists using the most modern techniques. No coincidence that the most common and important medical journals devote much time to the subject, publishing studies in several universities in the world. What's new in the field, out in a continuous stream.


It is seen for example that the active ingredient of the Crespino is a biological substance called Berberine (BBR), mainly present in the roots. The BBR fact, it acts by stimulating physiologically an enzyme body, indicated with the abbreviation AMPK. This protein plays a key role in our energy metabolism, counteracting the first adipoge-nesi (ie the formation of fat). Therefore acts in tandem with forskolin: on one hand it blocks the formation of lipids and on the other, as we have seen, it stimulates the destruction!

The Berberine also is essential for all those who suffer from metabolic syndrome (a collection of symptoms typical of someone who has a few extra pounds). The BBR is in fact able to reduce the bad cholesterol and increase the good one. Also counteracts alterations of glucose due to the excessive ingestion of food. In addition to these effects "metabolic", the Berberine able to do many other important things for our health. For example, just as the Coleus, is able to control the nervous hunger. The mechanism, however, is completely different compared to the forskolin.

It is therefore something more, certainly useful, because when you are on diet hunger is always great! The BBR, in particular, stimulates ie our tissues to produce a lipidic substance, called oleyl Etanol Amide (AEO). Even the AEO is able to influence the area of ​​the brain that controls the sense of hunger. And so we can better withstand even quell'irrefrenabile desire to eat that assails us from the first day that we put on a diet.

The benefits of Berberine, however, does not stop there. The BBR and found pure inhibitor of an enzyme called acetylcholinesterase. In practice favors muscle movement, which is essential part of any weight loss treatment. All Dieticians recommend to avoid it, if you really want to lose weight, a sedentary lifestyle, practicing a little 'motion and healthy exercise.


Berberine Forksolina and are among the active ingredients to the base of Eupondil,
manufactured by Alphrema.





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