THE PROPERTY COFFEE GREEN
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The varieties of coffee are numerous (about 60) and Coffea arabica L. contained in the product is among the most valuable species and famous. In green coffee, coffee bean that is in at the time of collection, the content of phenolic compounds is relevant and chlorogenic acid is the predominant substance (in fact constitutes 5-10% of the total). After fermentation and roasting, the residual content of chlorogenic acid drops 1 to 5%. The chlorogenic acid is the ester of caffeic acid with quinic acid and has gained particular interest in nutrition, has been studied for its antioxidant, antibacterial and antiviral properties and, in general, for potentially preventive activities against 2 diabetes, cancer and cardiovascular diseases. Recent studies also show how the consumption of green coffee is able to produce antihypertensive effects in vivo and in humans, improvements in human vasoreactivity, inhibitory effects on the accumulation of lipids and body weight and the modulation of glucose metabolism in humans.
Effects on blood sugar and fat mass
According to the most recent studies, the chlorogenic acid is able to reduce the absorption of sugars from the intestine and accelerate metabolism, accelerating the natural process by which our body burns fat accumulated. In vitro data suggest that chlorogenic acid and its metabolite, caffeic acid, are capable of inhibiting concentrations of amylase, effect on the gastrointestinal tract that causes the reduction of the absorption of glucose from starch, reducing calorie intake (de Sottillo et al., 2006). Always in vitro chlorogenic acid has been shown to delay the absorption of lipids in the intestine and to activate the metabolism of fat in the liver.
In animal models it has been shown that the consumption of green coffee is able to hinder the increase of body weight and visceral fat accumulation. Other animal experiments suggest that this phenol is able to mediate the antiobesity effects likely by inhibiting the accumulation of hepatic triglycerides (Shimoda et al., 2006). Other authors postulate that the antiobesity effect of chlorogenic acid is the result of mediation between plasma level of adipochina and distribution of body fat, in addition to the regulation of the synthesis of fatty acids and cholesterol. In a clinical study of 12 weeks on 30 overweight or obese subjects, it was observed the effect of coffee enriched with chlorogenic acids on glucose uptake and body mass. The mass loss in the group that had taken chlorogenic acid was 5.4 kg versus 1.7 kg in the group of regular coffee. The study indicates that chlorogenic acid, for the effect on the absorption and the use of glucose, can produce a significant reduction of body mass and fat mass (Thom, 2007). In a review (Onakpoya et al., 2010) was evaluated the effect of the assumption of green coffee in the reduction of body weight. In 3 RCTs, with 142 participants, there was a statistically significant difference in body weight between the consumatoridi green coffee and placebo. In a recent study (Vinson et al., 2012) has been evaluated the effect of the administration of chlorogenic acid in 16 subjects 22-26enni overweight. The participants were given daily, alternating, a low dose of green coffee extract (700 mg), a high dose (1,050 mg) or a placebo. At the end of the 22 weeks of the study, participants who received the high dose showed a mean weight loss of 7.7 kg, with a reduction of 10.5% of the total body weight and 16% body fat. And precisely: in 10 of the 16 participants was observed on 10% of weight loss, 5 in the 5% and 1 to 4%. One interesting fact: at the beginning of the study all subjects were classified as overweight, while at the end of 6 had a body mass index and a normal weight.
Hypertension
Chlorogenic acid, thanks to the antioxidant, can improve the bioavailability of nitric oxide favoring the improvement of endothelial dysfunction and vascular hypertrophy (Suzuki A et al., 2008). Are documented antihypertensive effects both in vivo and in humans following administration of chlorogenic acid. In one study (Watanabe et al., 2006) the administration of green coffee (140 mg / day) has shown efficacy in the reduction of blood pressure in 28 subjects with hypertension light.
Useful in case of:
• OVERWEIGHT
• HYPERGLYCEMIA
• HIGH BLOOD PRESSURE LIGHT
To use the product as an adjunct to diet for the control and reduction of body weight: the product does not replace a varied diet. It must be used as part of a reduced calorie diet adequate follow a healthy lifestyle with a good level of physical activity. If the diet is followed for a long time, longer than three weeks, you should seek the advice of your doctor.
Bibliography
• Joe A Vinson, Bryan R Burnham, Mysore V Nagendran. Randomized, double-blind, placebo-controlled, linear dose, crossover study to evaluate the efficacy and safety of a green coffee bean extract in overweight subjects. Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2012:5 21-27.
• Igho Onakpoya, Rohini Terry, and Edzard Ernst. The Use of Green Coffee Extract as aweight Loss Supplement: A Systematic Review andMeta-Analysis of Randomised Clinical Trials. Gastroenterology Research and Practice. Volume 2011, Article ID 382852, 6 pages.
• Hiroshi Shimoda, Emi Seki and Michio Aitani. Inhibitory effect of green coffee bean extract on fat accumulation and body weight gain in mice. BMC Complementary and Alternative Medicine, 2006, 6:9.
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