THE SECRET OF LONGEVITY IS IN STEM CELLS?

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There are currently 53 supercentenarians: people of 110 years or more, to date in life; and 51 of them are female.

Ben Dulken, Stanford University (California, USA), and colleagues have explored the possible reasons and likely to reach such an advanced age.

Based on current understanding of the behavior of stem cells, the researchers argue that there are fundamental differences in the decline among men and women: in particular as regards the sex hormones, estrogen and testosterone, in changing the life span. Previous studies on laboratory animals indicate that estrogen has a direct effect on stem cells in female mice, increasing the number of blood stem cells to improve the regenerative capacity of stem cells of the brain. In addition, supplementation of estrogen can increase the lifespan of male mice.

The study authors conclude that: "Longevity is different between the sexes, with females, in most mammals, including man, characterized by a greater lifespan. A feature of aging is the functional decline the stem cells. A key question is whether the aging of stem cells is different between males and females, and if this would have an effect on disease and lifespan. We must understand this important aspect. "

Source: Worldhealth

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