INTESTINAL BACTERIA: MAY ENCOURAGE THE INCREASE OF WEIGHT
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The presence of a specific intestinal bacteria coupled with a high fat diet can promote weight gain.
Michael Blaut, PhD, director of the German Institute of Microbiology Department of Human Nutrition gastrointestinal, and colleagues examined the role of the intestinal bacterium Clostridium ramosum into 3 groups of mice. The first group had a simplified human intestinal microbiota of 8 species of bacteria, including Clostridium ramosum; the second a simplified human intestinal microbiota with the exception of Clostridium ramosum, and only the third housed the ramosum Clostridium.
The mice were fed a high-fat diet or a low-fat diet for 4 weeks. The results showed that mice harboring Clostridium ramosum have gained weight when fed a high-fat diet. In contrast, mice that did not house Clostridium ramosum were less grssi even if fed a high-fat diet. All groups of mice fed a low-fat diet on the other hand, were thin, indicating that the effect of obesity Clostridium ramosum occurs only in combination with a high-fat diet.
The results also showed that mice harboring Clostridium ramosum also had the highest gene expression of glucose transporter 2 (Glut2), a protein that allows the absorption of glucose and fructose, and transport proteins of fat, including fatty acid translocase (CD36). "Our results indicate that Clostridium ramosum promotes the absorption of nutrients in the small intestine and thereby promotes obesity," he said Blaut.
Source: Worldhealth
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