Supplements for those who perform physical activity


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International Observatory of Oxidative Stress - Prof. Luigi Iorio

in particular: Chapter 5. The d-ROMs test in Sports Medicine. Review of clinical trials

    
Physical activity appears to be at the center of a new "paradox" scientific, after the French, called "the paradox of sport", because, depending on how it is done, it can be both powerful preventive weapon that causes pathology.

So, if a proper sports activities improves the quality of life and helps to reduce morbidity and mortality from cardiovascular disease, cancer and many chronic diseases, physical exercise incongruous alters the normal oxidative balance, predisposing to premature aging pathologies oxidative stress.

When it comes to exercise incongruous, it refers to the excess that is the lack of activity. For example, a sedentary lifestyle promotes overweight and obesity, conditions, both of which tend to be associated with higher average levels of ROM in serum compared with that in normal weight subjects.

In this regard, a comparative study has shown that a body mass index (BMI) greater than 30, a condition that corresponds to the degree of obesity according to the WHO classification, is associated with values ​​of the d-ROMs test significamene higher than those detected in the control group of normal weight (BMI <23), a parity of every other condition. On the other hand, various sporting disciplines that involve a considerable muscular effort, for the intensity and / or for the duration of the effort, is constantly accompany changes in levels of biochemical markers of oxidative stress that, in certain cases persist even after athletic performance or competitive engagement. So, even if you have need to distinguish between amateur and professional, and especially among those trained and untrained subjects, excessive physical activity is an undeniable and significant risk factor for oxidative stress.


Test to cicloegometro

Studies in subjects in good health have shown that after moderate exercise values ​​of the d-ROMs test tend to increase significantly compared to those observed at rest, but not over, however, the threshold value of 350 U CARR (equal to 28.00 mg H 2 O 2 / dL), but properly trained athletes have serum levels of ROM on average lower than those detected in untrained subjects. After maximal exercise (cycle ergometer test), however, the values ​​of the d-ROMs test increased indiscriminately, ie independently from training, exceeding the threshold above 350 U CARR.Tuttavia, an hour after this effort, while the subjects regularly trained rapidly return to their values, and in any case below 300 U CARR, the untrained subjects retain more persistently elevated over time their serum levels of ROM (> 350 U CARR). Similar results were found in a study of 10 volunteers subjected to the same test until the onset of cramps or muscle aches.

These data suggest that the smooth performance of the d-ROMs test can be useful in the "calibrate" the training and enabling more prolonged muscular effort to athletes without increasing the risk of injury from free radicals.




Supplements for those who perform physical activity

Antioxidant Supplements